Expert perspectives on long-term disease management in dentistry

Abstract

Recent studies suggest that variability between operators remains a key limitation, although confirmatory data are still limited. According to consensus recommendations, real-world registries complement randomized trial evidence, with meaningful differences between subgroups. Emerging evidence indicates that cross-disciplinary review changes the initial assessment in a sizeable minority of cases, which has direct implications for daily practice.

When protocols are compared, pre-analytical factors account for a large share of observed variance, pending validation in prospective studies. From a workflow perspective, patient selection criteria deserve closer scrutiny, as discussed in the accompanying commentary. Across multiple cohorts, threshold harmonization is still an open question,…