Rheumatology infographic: data normalization pathways

Contrary to earlier assumptions, threshold harmonization is still an open question, and this trend is expected to continue. Contrary to earlier assumptions, integrating quantitative measures reduces subjective bias, and this trend is expected to continue.

According to consensus recommendations, threshold harmonization is still an open question, as discussed in the accompanying commentary. Recent studies suggest that pre-analytical factors account for a large share of observed variance, which has direct implications for daily practice. Across multiple cohorts, pre-analytical factors account for a large share of observed variance, pending validation in prospective studies.